{"id":64074,"date":"2025-12-22T12:51:59","date_gmt":"2025-12-22T17:51:59","guid":{"rendered":"https:\/\/alumni.cornell.edu\/cornellians\/?p=64074"},"modified":"2025-12-22T12:52:00","modified_gmt":"2025-12-22T17:52:00","slug":"baker-institute-75th","status":"publish","type":"post","link":"https:\/\/alumni.cornell.edu\/cornellians\/baker-institute-75th\/","title":{"rendered":"Baker Institute Marks 75 Years of Helping Save Animals’ Lives"},"content":{"rendered":"\n

For three-quarters of a century, its researchers have battled diseases, developed vaccines, mapped genomes, and more<\/p>\n\n\n\n

Editor’s note: Thanks to the Baker Institute for sharing information from its anniversary timeline.<\/em><\/p>\n\n\n\n

By Beth Saulnier<\/strong><\/p>\n\n\n\n

For 75 years, Cornell\u2019s Baker Institute for Animal Health<\/a> has made key advances that have contributed to the wellbeing of dogs, cows, horses, and other species\u2014including humans. <\/p>\n\n\n\n

\"Three
Attendees at the Institute\u2019s dedication in 1951.\u00a0<\/figcaption><\/figure>\n\n\n\n

Located near campus on Ithaca\u2019s Snyder Hill, the facility was founded in 1950 as the Veterinary Virus Research Institute. <\/p>\n\n\n\n

Twenty-five years later\u2014after the passing of its founding director, veterinarian and virologist James \u201cDrew\u201d Baker, PhD \u201938, DVM \u201940\u2014it was renamed in his memory.<\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/p>\n\n\n\n

\n

In honor of its 75th birthday, here\u2019s a sampling of the institute\u2019s groundbreaking discoveries\u2014including many by Big Red alumni:<\/p>\n\n\n\n

First Vet Tissue-Culture Lab<\/strong><\/h2>\n\n\n\n

Five years after the institute\u2019s founding, it became home to the world\u2019s first tissue-culture laboratory established for veterinary use. That allowed researchers to cultivate a host-specific organism like infectious hepatitis without infecting dogs\u2014and to weaken live viruses in culture over time, greatly improving vaccine safety and predictability.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\n\n\n\n

<\/p>\n<\/div>

\"Portrait
Founding director James \u201cDrew\u201d Baker.<\/figcaption><\/figure><\/div>\n\n\n\n

A Cutting-Edge Vaccine<\/strong><\/h2>\n\n\n\n

In the 1960s, researchers developed a vaccine that immunizes dogs against both distemper and infectious hepatitis\u2014the first dual-virus vaccine for animals ever created.<\/p>\n\n\n\n

\n\n\n\n

Diagnostic Tests to Help Dog Breeders<\/strong><\/h2>\n\n\n\n

Also in the \u201960s, the institute discovered ways to test for infectious diseases that cause fertility problems in canines\u2014including work by Leland \u201cSkip\u201d Carmichael, PhD \u201959, who created a way to detect the Brucella<\/em> bacterium, which causes pregnancy loss.<\/p>\n\n\n\n

\n\n\n\n

<\/p>\n\n\n\n

The \u2018Coggins\u2019 Test<\/strong><\/h2>\n\n\n\n
\"Dr.
Leroy Coggins, PhD \u201962 (left), and colleagues with an equine patient.<\/figcaption><\/figure>\n\n\n\n

Named for the scientist (Leroy Coggins, PhD \u201962) who invented it in 1972, the test detects equine infectious anemia, and has been instrumental in controlling the deadly disease.<\/p>\n\n\n\n

\n\n\n\n

Battling Canine Parvo<\/strong><\/h2>\n\n\n\n
\"Five
Viral samples from the 1970s and \u201980s.<\/figcaption><\/figure>\n\n\n\n

Millions of animal lives have been saved thanks to the Baker researchers who quickly responded to the 1978 outbreak of a mysterious disease causing vomiting, severe diarrhea, and death in dogs worldwide. They not only created a diagnostic test for the culprit\u2014which would become known as canine parvovirus\u2014but developed the now-standard vaccine.<\/p>\n\n\n\n

\n\n\n\n

Studying the Dog Genome<\/strong><\/h2>\n\n\n\n

By mapping inherited diseases in purebreds, Baker scientists pioneered the field of canine genetics. In 1997, they published the first linkage map of the dog genome in the journal Genomics<\/em>\u2014offering a framework for identifying disease-causing mutations, not only in canines but in humans.<\/p>\n\n\n\n

\n\n\n\n

Reversing Canine (and Human!) Blindness<\/strong><\/h2>\n\n\n\n

In the early 2000s, Baker researchers were awarded a patent for a DNA-based test for a canine condition called congenital stationary night blindness\u2014and went on to develop the first gene therapy technique to reverse it. More than a decade later, the FDA approved a therapy, based on that early work, to treat a rare form of human blindness.<\/p>\n\n\n\n

\n\n\n\n

Equine Genome Sequencing<\/strong><\/h2>\n\n\n\n
\"Dr.
Genetics pioneer Doug Antczak \u201969 with Twilight.<\/figcaption><\/figure>\n\n\n\n

A mare named Twilight\u2014who was bred, born, and raised at Cornell\u2019s McConville Barn\u2014was the first horse to have its whole genome sequenced. <\/a>After a decade of work led by Doug Antczak \u201969, her 2.7 billion base pair genome was fully sequenced in the mid-2000s, serving as a worldwide resource.<\/p>\n\n\n\n

\n\n\n\n

Decoding Canine Hip Dysplasia<\/strong><\/h2>\n\n\n\n
\"An
Hip dysplasia seen on an x-ray.<\/figcaption><\/figure>\n\n\n\n

Biochemist George Lust, PhD \u201964, was recruited to the faculty to study the degenerative condition, which causes untold suffering in dogs. He spent decades researching the genetic and environmental factors that contribute to it\u2014and in 2007, his lab discovered the first markers enabling a genetic test for it.<\/p>\n\n\n\n

\n\n\n\n

Breakthroughs in Assisted Reproduction<\/strong><\/h2>\n\n\n\n
\"Dr.
Rachel Philipson<\/figcaption>
Researcher Jacque Nelson-Harrington\u00a0\u201902 at work in the lab of Prof. Alex Travis (center) in 2020.<\/figcaption><\/figure>\n\n\n\n

The offspring of a beagle mother and Lab father, Klondike was the first puppy in the Western Hemisphere to be born from a frozen embryo\u2014a breakthrough that aids threatened canine species, including some wolves. In 2015, two years after Klondike\u2019s arrival, the institute welcomed the first puppies ever born through IVF.<\/p>\n\n\n\n

(Top: A puppy born through IVF. All images provided, unless otherwise indicated.)<\/em><\/p>\n\n\n\n

Published December 22, 2025<\/p>\n\n\n\n

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